how are you

"Como você está?" is the standard, neutral way to ask someone about their well-being. The mental image is of someone pausing to check in on another person's current emotional or physical state, showing genuine interest in their life. While it is the most common translation for "how are you," it is slightly more personal than the very common "Tudo bem?" which often functions more like a greeting than a literal inquiry. In casual Brazilian Portuguese, you might often hear it shortened to "Como você tá?" or even just "E aí?".
In conversation
Checking in on a friend
Oi, João! Quanto tempo. Como você está?
Hi, João! Long time no see. How are you?
Oi, Ana! Estou bem, e você?
Hi, Ana! I'm well, and you?
This is a standard, polite way to reconnect with someone you haven't seen in a while.
After a long day
Você parece cansado, filho. Como você está?
You look tired, son. How are you?
Foi um dia puxado, mãe. Só preciso descansar.
It was a tough day, mom. I just need to rest.
Using this phrase shows empathy when you notice someone isn't their usual self.
Examples
Como você está hoje?
How are you today?
Diga-me, como você está se sentindo agora?
Tell me, how are you feeling right now?
Eu não te vejo há semanas, como você está, afinal?
I haven't seen you in weeks, how are you, after all?